Topical Nasal Decongestant Pharmaceutical Xylometazoline Hydrochloride 1218-35-5 Xylometazoline HCL

1.  Quick Detail:
 
English name: xylometazoline hcl
English Synonyms:  XYLOMETAZOLINE HYDROCHLORIDE; XYLOMETAZOLIN HYDROCHLORIDE
CAS: 1218-35-5
EINECS Number: 214-936-4
Formula: C16H25ClN2
MW: 280.8361
Molecular Structure:

Boiling point: 394.2 ° C at 760 mmHg
Flash Point: 192.2 ° C
Vapor Pressure: 4.56E-06mmHg at 25 ° C
Appearance: white powder
Assay: 99%

2.  Descriptions:
 

Xylometazoline (Pronunciation: Zylow-met-TAH-zoleen), also known as xylomethazoline, is a drug which is used as a topical nasal decongestant.It is applied directly into the nose, either as a spray or as drops.

Xylometazoline is marketed under many brand names (see below) but the most common by far is Otrivine. The standard adult solution strength is 0.1% w/v xylometazoline, and the dose for children under 12 is usually 0.05%.

It should not be used for too long a period of time, or rebound effect may occur after discontinuation (see: Rhinitis medicamentosa). It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

 
3.  Applications:

• Xylometazoline is used to help clear the stuffy, blocked up feeling in the nose and sinuses caused by colds and allergies such as hayfever.
• It is a type of decongestant.
• It is used to contract the blood vessels in the lining of the nose and sinuses, thereby decreasing blood flow and reducing swelling and the feeling of congestion. It also reduces the production of mucus, drying up a blocked and stuffy nose.
• In general this drug is used to clear a blocked nose and sinuses associated with colds, influenza and allergies such as hay fever.
• Benefits of being on this drug can include relief of congestion in the nose and sinuses.

HOW TO USE/TAKE

How often do I take it?

• Use xylometazoline exactly as your doctor or pharmacist has told you.
• Use this medication regularly in order to get the most benefit from it.
• Remember to use it at the same time each day - unless specifically told not to by your doctor.
• Certain medical conditions may require different dosage instructions as directed by your doctor.

What dose?

• Dosage is based on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.

Do I need to avoid anything?

• Xylometazoline will not affect your ability to drive or operate machinery. Do not use for more than seven days. Consult your doctor or pharmacist for more details.

When can I stop?

• Always complete the full course as prescribed by your doctor.

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