Steroid Drug Intermediates Hormone Supplements CAS 2268-98-6 Hydroxyprogesterone Acetate

1.  Quick Detail:

English name: 11-A-acetoxyprogesterone
English Name: Hydroxyprogesteroneacetate; 11alpha-Hydroxyprogesterone acetate; (11alpha) -3,20-dioxopregn-4-en-11-yl acetate; 3,20-dioxopregn-4-en-11-yl acetate
CAS: 2268-98-6
Formula: C23H32O4
MW: 372.4978
Molecular Structure:

Density: 1.14g / cm3
Boiling point: 494.3 ° C at 760 mmHg
Flash Point: 213.5 ° C
Vapor Pressure: 6.54E-10mmHg at 25 ° C

Assay:99%

Appearance: White crystalline powder

 
2.  Description:

Hydroxyprogesterone caproate is a synthetic, steroidal progestin that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative hydroxyprogesterone formed from caproic acid (hexanoic acid).

Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.

The US FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention ofpreterm delivery in women with a history of preterm delivery, sparking a pricing controversy.

3. Uses: 

The use of hydroxyprogesterone caproate in pregnancy to prevent preterm birth in women with a history of preterm delivery between 20 weeks and 36 weeks and 6 days is supported by the Society of Maternal Fetal Medicine Clinic Guidelines put out in May 2012 as Level I and III evidence, Level A recommendation.Level I evidence refers to a properly powered randomized controlled trial, and level III evidence is support from expert opinion, while a Level A recommendation confers that the recommendation is made based on good and consistent scientific evidence. hydroxyprogesterone caproate 250 mg IM weekly preferably starting at 16–20 weeks until 36 weeks is recommended. In these women, if the transvaginal ultrasound cervical length shortens to <25 mm at < 24 weeks, cervical cerclage may be offered. In the 2013 study the guideline recommendation is based on by there was also a significant decrease of neonatal morbidity including lower rates ofnecrotizing enterocolitis (0 in treatment group vs 4 in control), intraventricular hemorrhage (4 in the treatment group compared with 8 in the control for relative risk of 0.25), and need for supplemental oxygen (14% in treatment group vs 24% in placebo for relative risk of 0.42). Furthermore, this study contained 463 patients, 310 of whom received injection. Of these patients, 9 had infants with congenital malformations (2%), but there was no consistent pattern and none involved internal organs.

Professional Manufacture: HONGKONG YUANCHENG GONGCHUANG TECHNOLOGY CO., LIMITED
is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid
injectable liquids, peptides,pharmaceutical raw materials & its intermediate.Our factory is in Nanhu Shouyi
Industrial District, just by the side of the beautiful South Lake in Wuhan. Our company integrates R&D,
producing, operating and marketing into an organic whole. All products are produced under
GMP conditions according to Standard Operation Procedure(SOP),not from little underground labs or black markets, so the quality is guaranteed. We have authority of export and import, and have experience of export for more than 10 years.

Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.

Payment Method: Western Union,Money Gram,T/T.
 
Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.

Discreetly Packing: Safe and professional disguised package can be guaranteed.

Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of steroid powder per month.

High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%,  As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

The more details of our product, please feel free to contact us!

Website:www.steroidhormonespowder.com
Contact Person: Lynn
Email : beststeroids@chembj.com
Skype : best.steroids
Phone : 852-23866694
Mobile : 852-53617701