YuanTong Biotech Co., Ltd
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| Product Name: | Levonorgestrel; Norgestrel (L-),D (minus) -norgestrel;797-63-7,Female Hormone Steroid Powder,Progesterone Hormones | Assay: | 99% |
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| Standard: | USP | ||
| High Light: | progesterone hormone,progesterone medicine |
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1. Quick Detail:
English name: D (minus) -norgestrel
Synonyms: Levonorgestrel; Norgestrel (L-)
CAS: 797-63-7
EINECS Number: 212-349-8
Formula: C21H28O2
Molecular Weight: 312.45
Molecular Structure:
Density: 1.13g / cm3
Melting point: 206 ℃
Boiling point: 459.1 ° C at 760 mmHg
Flash Point: 195.4 ° C
Vapor Pressure: 2.32E-10mmHg at 25 ° C
Uses:Progesterone medicines for irregular menstruation, uterine functional bleeding, endometriosis, etc.
Assay: 99%
Appearance: White crystalline powder
2. Description:
Levonorgestrel (or l-norgestrel or D-norgestrel) (Plan B, Next Choice, Postinor, "the morning after pill," and others) is a second generation progestin (synthetic progestogen) used as an active ingredient in some hormonal contraceptives, includingcombined oral contraceptive pills, progestogen only pills, emergency contraceptive pills, intrauterine systems, contraceptive implants, and hormone replacement therapy.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basichealth system.
3. Applications:
At low doses, levonorgestrel is used in monophasicand triphasicformulations of combined oral contraceptive pills, with available monophasic doses ranging from 100-250μg, and triphasic doses of 50μg/75μg/125μg.
At very low daily dose of 30μg, levonorgestrel is used in some progestogen only pillformulations.
Levonorgestrel is used in emergency contraceptive pills(ECPs), both in a combined Yuzpe regimenwhich includes estrogen, and as a levonorgestrel-only method. The levonorgestrel-only method uses levonorgestrel 1.5mg (as a single dose or as two 0.75mg doses 12 hours apart) taken within 3 days of unprotected sex, with one study indicating that beginning as late as 120 hours (5 days) after intercourse could be effective.
The primary mechanism of action of levonorgestrel as a progestogen-only emergency contraceptive pill is, according to FIGO, to prevent fertilization by inhibition of ovulation. The International Federation of Gynecology and Obstetrics(FIGO) has issued a statement that: "review of the evidence suggests that LNG [levonorgestreol] ECPs cannot prevent implantation of a fertilized egg. Language on implantation should not be included in LNG ECP product labeling." In June 2012, a New York Timeseditorial called on the Food and Drug Administration(FDA) to remove from the label the unsupported suggestion that levonorgestrel emergency contraceptive pills inhibit implantation. In November 2013, the European Medicines Agency(EMA) approved a change to the label for HRA Pharma's NorLevo saying it cannot prevent implantation of a fertilized egg. In November 2013, the EMA also approved a change to the label for HRA Pharma's NorLevo saying: "In clinical trials, contraceptive efficacy was reduced in women weighing 75 kg [165 pounds] or more, and levonorgestrel was not effective in women who weighed more than 80 kg [176 pounds]." In November 2013 and January 2014, the FDA and the EMA said they were reviewing whether increased weight and body mass index(BMI) reduce the efficacy of emergency contraceptives.
4. Specifications:
COA:
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Items |
Specification |
Results |
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Description |
White or practically white crystalline powder |
White crystalline powder |
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Specific Rotation |
30°~-35° |
32° |
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Melting Range |
232~239°C, and melting range is not more then 4°C |
234~238°C |
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identification |
It complies with the test for specific optical rotation and melting point |
Conforms |
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Infrared absorption spectrophotometry should be consistent with levonorgestrel CRS |
Conforms |
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Loss on drying |
≤0.5% |
0.20% |
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Residue on ignition |
≤0.3% |
0.07% |
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Limit of Ethynyl Group |
7.81%~8.18% |
7.92% |
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Related substances |
Single impurity ≤0.5% |
single impurity<0.5% |
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Total Impurities ≤2.0% |
Total impurities<2.0% |
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Organic Volatile impurties |
Ethanol ≤5000ppm |
1200ppm |
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Assay |
The product complies with specification in USP34 |
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Particle Size |
D(0.9)<10μm |
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Storage Condition |
Sealed, protect from light |
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5. Other Products:
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Progesterone Hormone Powders |
Progesterone |
Ethisterone |
6. Our Competitive Advantage:
Professional Manufacture: Shenzhen Keray Biotech CO., LIMITED
is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid
injectable liquids, peptides,pharmaceutical raw materials & its intermediate.O Our company integrates R&D,
producing, operating and marketing into an organic whole. All products are produced under
GMP conditions according to Standard Operation Procedure(SOP),not from little underground labs or black markets, so the quality is guaranteed. We have authority of export and import, and have experience of export for more than 10 years.
Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.
Payment Method: Western Union,Money Gram,T/T.
Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.
Discreetly Packing: Safe and professional disguised package can be guaranteed.
Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of steroid powder per month.
High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
For more information, please contact Sylvia.
Email: silvia.young@outlook.com
Phone: +86 13418710728
Whatsapp/Skype: +86 13418710728.
Contact Person: sinopeptides
Tel: +8613554447383
