Cancer Treatment Steroid Hormone Drug Intermediates CAS 68-96-2 17A-hydroxyprogesterone

1.  Quick Detail:

Steroid Hormone Drug Intermediates Glucocortocoid Steroids CAS 68-96-2 17A-hydroxyprogesterone

2.  Description:

English Name: 17A-hydroxyprogesterone
English Name: 17-Alpha-Hydroxy-Progesterone; 17-alpha-hydroxypregn-4-ene-3,20-dione; 17alpha-Hydroxyprogesterone; Hydroxyprogesterone; 17α-Hydroxy Progesterone
CAS: 68-96-2
EINECS Number: 200-699-4
Formula: C21H30O3
MW: 330.4611
Molecular Structure:

Density: 1.15g / cm3
Melting point: 276 ℃
Boiling point: 482.9 ° C at 760 mmHg
Flash Point: 259.9 ° C
Vapor Pressure: 2.37E-11mmHg at 25 ° C
Uses:Used as a steroid hormone drug intermediates

Assay:99%

Appearance:White crystalline powder

3. Applications:

The 17-hydroxyprogesterone (17-OHP) test is routinely ordered as part of newborn screening in the UnitedStates to detect congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. CAH is a group ofinherited disorders caused by specific gene mutations and associated with cortisol-related enzymedeficiencies. About 90% of CAH cases are caused by a mutation in the 21-hydroxylase gene (also calledP450c1 or CYP21A2) and may be detected due to the accumulation of 17-OHP in the blood.
The 17-OHP test may be used to screen for CAH in older children or adults before symptoms appear or toconfirm a CAH diagnosis in people with symptoms.

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