Shenzhen Keray Biotech Co., Ltd

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High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate

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High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate

China High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate supplier
High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate supplier High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate supplier

Large Image :  High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate

Product Details:

Place of Origin: China
Brand Name: GC
Certification: KOSHER/ISO9001/SGS
Model Number: 65-28-1

Payment & Shipping Terms:

Minimum Order Quantity: 100g
Price: Negotiation
Packaging Details: As your requirements
Delivery Time: After receipt of your payment
Payment Terms: Western Union,Money Gram or T/T
Supply Ability: 1000 kg per month
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Detailed Product Description
Manufacturer: GC Product Name: VASOMAX;phentolaminemethanesulphonate; Phentolamine Methanesulfonate; Phentolamine Methanesulfonate Salt; Phentolamine Mesilate;65-28-1;Phentolamine Mesylate;Adrenergic Blocking Medication;Pharmaceutical Raw Materials;
Assay: 99% Standard: USP
Contact Person: Lynn Email: Beststeroids@chembj.com
Skype: Best.steroids Phone: 852-23866694
Mobile: 852-53617701

1.  Quick Detail:


 English name: Phentolamine Mesylate
Alias: VASOMAX;phentolaminemethanesulphonate; phentolamine methanesulfonate; Phentolamine methanesulfonate salt; phentolamine mesilate
CAS: 65-28-1
EINECS Number: 200-604-6
Formula: C18H23N3O4S
MW: 377.4579
Molecular Structure:

 

High Purity Pharmaceutical Raw Materials Adrenergic Blocking Medication 65-28-1 Phentolamine Mesylate


Melting point: 180-182 ℃
Boiling point: 551 ° C at 760 mmHg
Flash Point: 287 ° C
Water-soluble: 50 mg / mL
Vapor Pressure: 9.48E-13mmHg at 25 ° C

Appearance: white powder
Assay: 99%


2.  Descriptions:
 

Phentolamine mesylate (OraVerse), a nonselective a-adrenergic blocking drug, is the first therapeutic agent marketed for the reversal of soft-tissue anaesthesia and the associated functional deficits resulting from an intraoral submucosal injection of a local anaesthetic containing a vasoconstrictor. In clinical trials, phentolamine injected in doses of 0.2 to 0.8 mg (0.5 to 2 cartridges), as determined by patient age and volume of local anaesthetic administered, significantly hastened the return of normal soft-tissue sensation in adults and children 6 years of age and older. Median lip recovery times were reduced by 75 to 85 minutes. Functional deficits, such as drooling and difficulty in drinking, smiling, or talking--and subjects' perception of altered function or appearance--were consistently resolved by the time sensation to touch had returned to normal. Adverse effects of phentolamine injected in approved doses for reversal of local anaesthesia in patients ranging in age from 4 to 92 years were similar in incidence to those of sham injections, and no serious adverse events caused by such use were reported. The clinical use of phentolamine is viewed favorably by dentists who have administered the drug and by patients who have received it. Optimal use may require some modifications of the technique described in the package insert; cost of the agent may be influencing its widespread adoption into clinical practice. Phentolamine mesylate, in the form of OraVerse (Novalar Pharmaceuticals, San Diego, USA) represents a new therapeutic class of drugs in dentistry intended to reverse soft-tissue anaesthesia after nonsurgical dental procedures (e.g., restorative or deep scaling/root planing procedures). As shown in Figure 1, OraVerse is manufactured in 1.7 mL dental cartridges, each of which contains 0.4 mg active drug. This review describes the development of phentolamine as a dental drug, its pharmacologic characteristics, and how it may be used in clinical practice to improve patient care.

 
3.  Applications:

Prevention or control of hypertensive episodes in patients with pheochromocytoma (excluding OraVerse ); pharmacologic test for pheochromocytoma (not method of choice) (excluding OraVerse ); prevention and treatment of dermal necrosis and sloughing following IV administration or extravasation of norepinephrine (excluding OraVerse ); reversal of soft-tissue anesthesia (ie, anesthesia of lip and tongue) ( OraVerse only).

 

4.  Other Products:
 
 

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4-Amino -5-chloro-2-ethoxy-N- benzamide
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5.  Our Competitive Advantage:
 

Professional Manufacture: HONGKONG YUANCHENG GONGCHUANG TECHNOLOGY CO., LIMITED
is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid
injectable liquids, peptides,pharmaceutical raw materials & its intermediate.Our factory is in Nanhu Shouyi
Industrial District, just by the side of the beautiful South Lake in Wuhan. Our company integrates R&D,
producing, operating and marketing into an organic whole. All products are produced under
GMP conditions according to Standard Operation Procedure(SOP),not from little underground labs or black markets, so the quality is guaranteed. We have authority of export and import, and have experience of export for more than 10 years.

Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.
Payment Method: Western Union,Money Gram,T/T.
 
Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.

Discreetly Packing: Safe and professional disguised package can be guaranteed.
Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of steroid powder per month.
High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%,  As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
 

Contact Details
Shenzhen Keray Biotech Co., Ltd

Contact Person: silvia.young

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