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|Manufacturer:||GC||Product Name:||Mifepriston,Mifepristone,Mifepriston Dianhydride,84371-65-3,Progesterone Hormones,Antiprogestogens|
1. Quick Detail:
English name: mifepristone
English Name: Mifepriston Dianhydride; (11R, 13S, 17S) -11- (4-dimethylaminophenyl) -17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11, 12,14,15,16-decahydrocyclopenta [a] phenanthren-3-one
Density: 1.18g / cm3
Boiling point: 628.6 ° C at 760 mmHg
Flash Point: 334 ° C
Vapor Pressure: 1.14E-16mmHg at 25 ° C
Uses:As anti-pregnancy drugs
Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4,9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist, and has occasionally been used in refractory Cushing's syndrome (due to ectopic/neoplastic ACTH/cortisol secretion). During early trials, it was known as RU-38486 or simply RU-486, its designation at the Roussel Uclaf company, which designed the drug. The drug was initially made available in France, and other countries then followed—often amid controversy. It is marketed under tradenames Korlym and Mifeprex, according to FDA Orange Book.
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group, however, was the discovery and development of compounds with antiglucocorticoid properties. These antiglucocorticoid properties are of great interest in the treatment of severe mood disorders and psychosis, although a review of published articles was inconclusive on their efficacy, and considered the use of these drugs in mood disorders at 'proof of concept' stage. It is on the World Health Organization's List of Essential Medicines.
Mifepristone is used alone or in combination with misoprostol (Cytotec) to end an early pregnancy. Early pregnancy means it has been 49 days or less since your last menstrual period began. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.
Mifepristone is also available as another product (Korlym), which is used to control hyperglycemia (high blood sugar) in people with a certain type of Cushing's Syndrome in which the body makes too much of the hormone cortisol. This monograph only gives information about mifepristone (Mifeprex), which is used alone or in combination with another medication to end an early pregnancy. If you are using mifepristone to control hyperglycemia caused by Cushing's syndrome, read the monograph entitled mifepristone (Korlym) that has been written about this product.
|Ref. Standard||According to the CP 2010 version and enterprise internal control standard inspection|
|Results Of Analysis Tests|
|Description||Light Yellowish Crystalline Powder||Light Yellowish Crystalline Powder|
|Specific Rotation||+124°~ +129°||+127.1°|
|(HPLC) Related substances||(1)(Single):≤0.5%||0.31%|
|Loss On Drying||≤0.5%||0.1%|
This product conforms to the CP 2010 and enterprise internal control
5. Other Products:
Progesterone Hormone Powders
6. Our Competitive Advantage:
Professional Manufacture: HONGKONG YUANCHENG GONGCHUANG TECHNOLOGY CO., LIMITED
is a legit and professional pharmaceutical manufacturer specialized in steroid hormone powders, steroid
injectable liquids, peptides,pharmaceutical raw materials & its intermediate.Our factory is in Nanhu Shouyi
Industrial District, just by the side of the beautiful South Lake in Wuhan. Our company integrates R&D,
producing, operating and marketing into an organic whole. All products are produced under
GMP conditions according to Standard Operation Procedure(SOP),not from little underground labs or black markets, so the quality is guaranteed. We have authority of export and import, and have experience of export for more than 10 years.
Minimum Order: 10-100 grams.our min packing of each powder is 10g or 100g, but some expensive powder can be bought at several grams.
Payment Method: Western Union,Money Gram,T/T.
Professional Delivery: By courier ( EMS, DHL, Fedex, UPS,TNT) is prefered, bulk order can be negotiated.5-7 business days delivery in timely manner. Tracking No. is available ,we can provide you latest tracking of our customers to check validity of delivery if you need.
Discreetly Packing: Safe and professional disguised package can be guaranteed.
Plenty In Stock: Most of powders are in stock.We export over 1000 kilograms of steroid powder per month.
High Delivery Rate: Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.